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Planta Med 1988; 54(4): 315-317
DOI: 10.1055/s-2006-962443
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© Georg Thieme Verlag Stuttgart · New York

Study on the Alkaloids of Melodinus tenuicaudatus

Y. L. Zhou1 , J. H. Ye1 , Z. M. Li2 , Z. H. Huang1
  • 1Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 319 Yue-yang Road, Shanghai 200031, Peoples' Republic of China.
  • 2Yunnan Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan province, Peoples' Republic of China.
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Publication History

1987

Publication Date:
24 January 2007 (online)

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Abstract

Fourteen alkaloids were isolated from the stem bark of Melodinus tenuicaudatus Tsiang et P. T. Li. Eleven of them were identified as known alkaloids, namely, scandine (2), Δ14-eburnamine (4), vindolinine N b-oxide (5), 11-methoxytabersonine (6), vindolinine (7), epi-vindolinine N b-oxide (8), hazuntine (9), compactinervine (10), 11-hydroxytabersonine (11), Δ14-vincine (12), and normacusine B (14). Two alkaloids were new: 10-hydroxyscandine (1), and the dimer, tenuicausine (3); their structures were elucidated by spectroscopic and chemical methods. One alkaloid (13) occurring in trace amounts, could not be identified.