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Planta Med 1987; 53(1): 8-12
DOI: 10.1055/s-2006-962605
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© Georg Thieme Verlag Stuttgart · New York

Hypoglycemic Activity of Twenty Plant Mucilages and Three Modified Products[1]

Masashi Tomoda2 , Noriko Shimizu2 , Yoshiteru Oshima3 , Michiko Takahashi3 , Miki Murakami3 , Hiroshi Hikino3
  • 2Kyoritsu College of Pharmacy, Shibakoen, Minato-ku, Tokyo, Japan.
  • 3Pharmaceutical Institute, Tohoku University, Aoba-yama, Sendai, Japan.
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Publication History

1986

Publication Date:
24 January 2007 (online)

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Abstract

Twenty water-soluble mucilages obtained from plants in the Liliaceae, Amaryllidaceae, Dioscoreaceae, Orchidaceae, Saxifragaceae, Malvaceae and Plantaginaceae families were tested for the hypoglycemic activity on administration to normal mice. Considerable activity was observed for most of the mucilages isolated from plants in the Malvaceae family. They have the repeating structure (1→4)-[O-β-(D-glucopyranosyluronic acid)-(1→3)]-O-α-(D-galactopyranosyluronic acid)-(1→2)-O-α-L-rhamnopyranose in their main parts. The deacetylated product of Plantago-mucilages A, the main mucilage present in the seed of Plantago asiatica, also showed remarkable hypoglycemic activity.

1 Antidiabetes drugs. Part 25. Also Part 115 on the validity of the Oriental medicines.

1 Antidiabetes drugs. Part 25. Also Part 115 on the validity of the Oriental medicines.