Specific Radioimmunoassay for Vincristine

Aarre Huhtikangas; Timo Lehtola; Seppo Lapinjoki; Mauri Lounasmaa

doi:10.1055/s-2006-962628

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Planta Med 1987; 53(1): 85-87
DOI: 10.1055/s-2006-962628

Full Papers

Specific Radioimmunoassay for Vincristine

Aarre Huhtikangas¹ , Timo Lehtola¹ , Seppo Lapinjoki¹ , Mauri Lounasmaa²

¹Department of Pharmaceutical Chemistry, University of Kuopio, POB 6, SF-70211 Kuopio, Finland.
²Department of Chemistry, Technical University of Helsinki, SF-02150 Espoo, Finland.

Further Information

Publication History

1986

Publication Date:
24 January 2007 (online)

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Abstract

A radioimmunoassay has been developed for vincristine (1), one of the bis-indole alkaloids of Catharanthus roseus. The high vincristine (1) specificity obtained is demonstrated by a low cross-reactivity of vinblastine (2), an alkaloid closely related to vincristine (1) in structure.