Abstract
Citracridone-I (Citra-I), a new acridone alkaloid from the root barks of Citrus depressa, was examined to evaluate toxicity in mice as well as blood pressure and small intestinal propulsion of rats in vivo. The antispasmodic effects of Citra-I were also investigated in the isolated ileum and vas deferens of guinea pig as well as uterine muscle of rat.