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Planta Med 1987; 53(3): 280-284
DOI: 10.1055/s-2006-962706
DOI: 10.1055/s-2006-962706
Full Papers
© Georg Thieme Verlag Stuttgart · New York
Effect of Sterol Inhibitors on the Incorporation of 14 C-Isopentenyl Pyrophosphate into Artemisinin by a Cell-Free System from Artemisia annua Tissue Cultures and Plants
Further Information
Publication History
1986
Publication Date:
24 January 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/198703/lookinside/thumbnails/10.1055-s-2006-962706-1.jpg)
Abstract
A cell-free system from Artemisia annua L. shoot cultures and plants (shoots and roots) which is capable of incorporating 14 C-isopentenyl pyrophosphate (14 C-IPP) into artemisinin has been developed. The sterol inhibitors miconazole, AMO 1618, CCC, and MER 29 increased both the incorporation of 14 C-IPP into artemisinin by cell-free extracts and the production of artemisinin in shoot cultures of Artemisia annua.