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Planta Med 1987; 53(6): 517-520
DOI: 10.1055/s-2006-962799
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© Georg Thieme Verlag Stuttgart · New York

Spasmolytic Activity of Angelicin: A Coumarin from Heracleum thomsoni 1

G. K. Patnaik, K. K. Banaudha, Khalid A. Khan, A. Shoeb, B. N. Dhawan
  • Central Drug Research Institute, Post Box No. 173, Lucknow 226001, India.
1 CDRI Communication No. 3981
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Publication History

1987

Publication Date:
24 January 2007 (online)

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Abstract

Angelicin, a coumarin isolated from the aerial parts of Heracleum thomsoni, showed nonspecific spasmolytic activity in a variety of in vivo and in vitro test models and was also orally active. In most of the test systems it was found to be equipotent to papaverine.