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J Reconstr Microsurg 1997; 13(2): 99-106
DOI: 10.1055/s-2007-1000224
DOI: 10.1055/s-2007-1000224
ORIGINAL ARTICLE
© 1997 by Thieme Medical Publishers, Inc.
End‐To‐Side Neurorrhaphy: a Histologic and Morphometric Study of Axonal Sprouting into an End‐To‐Side Nerve Graft
Weitere Informationen
Publikationsverlauf
Accepted for publication 1996
Publikationsdatum:
08. März 2008 (online)
ABSTRACT
This study investigated axonal regeneration in a denervated nerve graft sutured end-to-side with a main peripheral nerve trunk. To demonstrate morphologic changes, the peroneal nerve was severed in a rat and coapted end-to-side to the posterior tibial nerve. The integrity of the epineurial and perineurial sheath was altered in four different groups. Histologic evaluation 30 days after operation showed axonal regeneration in the nerve graft in all groups. Morphometric analysis of cross sections of the grafted nerve elucidated the importance of severance of the perineurium in end-to-side neurorrhaphy.