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Horm Metab Res 1994; 26(6): 297-300
DOI: 10.1055/s-2007-1001687
Originals Clinical

© Georg Thieme Verlag, Stuttgart · New York

Effects of Exercise Training on Plasma Androgens in Men

J. A. Houmard, C. McCulley, M. H. Shinebarger, N. J. Bruno
  • Human Performance Laboratory, East Carolina University, Greenville, North Carolina, U.S.A.
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Publication History

1993

1994

Publication Date:
14 March 2008 (online)

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Summary

An increased risk for coronary artery disease (CAD) is associated with a reduced plasma androgen concentration in men. The purpose of the present study wasto determine if plasma testosterone (T), sex hormone-binding globulin (SHBG), and dehydroepiandrosterone sulfate (DHEAS) concentration were altered with an exercise training program which reduced CAD risk. Thirteen men (mean±SE, age 47.2±1.5 yrs) were examined before and after 14 weeks of endurance-oriented physical training (3-4 days/week, 30-45 min/day). There were no changes in basal plasma T, SHBG and DHEAS concentration despite a significant (p<0.05) increase in insulin sensitivity, plasma HDL cholesterol, and a decrease in plasma triglyceride and adiposity. Exercise training thus appears to reduce CAD risk irrespective of androgen concentration in men.

Key words

Dehydroepiandrosterone Sulfate - Physical Activity - Sex Hormone-Binding Globulin - Testosterone