Summary
An increased risk for coronary artery disease (CAD) is associated with a reduced plasma
androgen concentration in men. The purpose of the present study wasto determine if
plasma testosterone (T), sex hormone-binding globulin (SHBG), and dehydroepiandrosterone
sulfate (DHEAS) concentration were altered with an exercise training program which
reduced CAD risk. Thirteen men (mean±SE, age 47.2±1.5 yrs) were examined before and
after 14 weeks of endurance-oriented physical training (3-4 days/week, 30-45 min/day).
There were no changes in basal plasma T, SHBG and DHEAS concentration despite a significant
(p<0.05) increase in insulin sensitivity, plasma HDL cholesterol, and a decrease in
plasma triglyceride and adiposity. Exercise training thus appears to reduce CAD risk
irrespective of androgen concentration in men.
Key words
Dehydroepiandrosterone Sulfate - Physical Activity - Sex Hormone-Binding Globulin
- Testosterone
