Horm Metab Res 1993; 25(5): 271-274
DOI: 10.1055/s-2007-1002095
Originals Clinical

© Georg Thieme Verlag, Stuttgart · New York

Transient Neonatal Hypercholesterolemia

Lack of Relationships with Dehydroepiandrosterone SulfateM. R. Averna1 , C. M. Barbagallo1 , G. Di Paola2 , F. P. La Placa1 , V. Scafidi1 , U. Dimita2 , A. Notarbartolo1
  • 1Istituto di Medicina Interna e Geriatria, Cattedra di Medicina Interna, Università di Palermo, Italy
  • 2Divisione di Neonatologia, Ospedale Buccheri La Ferla Fatebenefratelli, Palermo, Italy
Further Information

Publication History

1992

1992

Publication Date:
14 March 2008 (online)

Summary

In order to obtain new information about the relationship between transient neonatal hypercholesterolemia and adrenal gland function, we have studied 39 healthy babies found hypercholesterolemic at birth and 39 healthy controls with normal cholesterol levels. The results of this study have shown that levels of dehydroepiandrosterone sulfate in cord blood were not significantly different in the hypercholesterolemic subjects compared with normolipidemic controls (1.4±0.5 μg/dl vs 1.3±0.5 μ/dl). Moreover correlations between this hormone and levels of total and LDL-cholesterol were not only not statistically significant but even positive (respectively r = +0.207 and +0.195). These data suggest that dehydroepiandrosterone sulfate measurements in cord blood do not give any further information about transient neonatal hypercholesterolemia.