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Horm Metab Res 1992; 24(9): 409-411
DOI: 10.1055/s-2007-1003347
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© Georg Thieme Verlag, Stuttgart · New York

Red Cell Membrane Protein Lateral Mobility in Diabetes Mellitus

G. Caimi, A. Serra, R. Lo Presti, A. Sarno
  • Istituto di Clinica Medica e Malattie Cardiovascolari, Università di Palermo, Palermo, Italy
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Publikationsverlauf

1991

1992

Publikationsdatum:
14. März 2008 (online)

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Summary

In a group of 24 diabetics subdivided for type, we evaluated the red cell membrane protein lateral mobility marking intact red cells with pyrene-3-maleimide (3-PM) and calculating the dimer to monomer fluorescence intensity ratio (Iex/Im). The same fluorescent parameter was determined in a group of 13 normal controls. From the obtained data, it is evident that the red cell membrane protein lateral mobility clearly discriminates normals from diabetics of type 1 and 2. In normals and in diabetics of type 1 and 2 no relationship is present between this fluorescent determinant and the glycometabolic parameters (FBGL and HbA1c); considering all the diabetics, a negative relationship is evident between Iex/Im ratio and HbA1c only.

Key words

Red Cell Membrane Proteins - Diabetes Mellitus