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Endoscopy 1997; 29(2): 120-124
DOI: 10.1055/s-2007-1004086
Case Report

© Georg Thieme Verlag KG Stuttgart · New York

Botulinum Toxin Injection as a Diagnostic Tool for Verification of Sphincter of Oddi Dysfunction Causing Recurrent Pancreatitis

S. M. Muehldorfer, E. G. Hahn, C. Ell
  • Dept. of Medicine I, University of Erlangen-Nuremberg, Erlangen, Germany
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Publication Date:
17 March 2008 (online)

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Abstract

Sphincter of Oddi dyskinesia (SOD) is among the less frequent causes of acute recurrent pancreatitis. We report on a patient with frequent pain attacks accompanied by pancreatic enzyme elevation, in whom a transitory decrease of the SO pressure following endoscopic botulinus toxin injection was a diagnostic clue for SOD.

The patient's symptoms resolved for 4 months, after which time recurrent symptoms paralleled the reoccurrence of the elevated SO pressure. Endoscopic sphincterotomy of the biliary sphincter relieved her symptoms for the subsequent follow-up period which is now 10 months.