Abstract
Background and Study Aims: We studied the clinical features and therapeutic outcome in patients with a diagnosis
of Dieulafoy lesion.
Patients and Methods: Twenty-six patients who had upper gastrointestinal bleeding from Dieulafoy lesions
received endoscopic therapy. The clinical and endoscopic features, and the outcome
of therapy, were analysed retrospectively.
Results: Hemostasis was attempted by hemoclipping in 18 patients, heater probe in six patients
and ethanol injection in two patients. The initial therapy was successful in 22 (84.6 %)
cases. Hemostasis was achieved with additional endoscopic therapy in three cases (11,5 %).
Surgical treatment was needed only in one case, owing to uncontrolled bleeding. One
patient died during the hospital stay from a cause unrelated to the Dieulafoy lesion.
There were no side effects related to endoscopic therapy. None of these patients presented
with rebleeding from Dieulafoy lesions over a mean long-term follow-up of 36 months.
Conclusions: Bleeding from Dieulafoy lesions can be managed successfully by endoscopic methods,
and these should be regarded as the first choice in their management. We emphasize
the role of hemoclipping, a mechanical method, for the endoscopic treatment of these
lesions.
