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Horm Metab Res 1990; 22(9): 467-469
DOI: 10.1055/s-2007-1004949
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© Georg Thieme Verlag, Stuttgart · New York

Hormonal Manipulation and Neonatal Imprinting of Carbonic Anhydrase Isozymes in Rat Liver

S. Jeffery1 , C. A. Wilson2 , N. D. Carter1
  • 1Department of Child Health, St. George's Hospital Medical School, London, United Kingdom
  • 2Department of Obstetrics and Gynaecology, St. George's Hospital Medical School, London, United Kingdom
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Publication History

1989

1990

Publication Date:
14 March 2008 (online)

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Summary

Thyroidectomy has a feminizing effect on the carbonic anhydrase isozymes II and III in male rat liver. These isozymes are known to be sexually differentiated but no treatment so far administered has produced total feminization and this is also true for thyroidectomy. Neonatal castration, however, does produce this result, suggesting the possibility of androgen imprinting for these isozymes during the neonatal period.

Key words

Carbonic Anhydrase - Thyroidectomy - Neonatal Imprinting