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Horm Metab Res 1989; 21(5): 272-274
DOI: 10.1055/s-2007-1009210
DOI: 10.1055/s-2007-1009210
Clinical
© Georg Thieme Verlag, Stuttgart · New York
Evidence of 1lβ-Hydroxylase Deficiency in a Patient with Cortical Adrenal Adenoma
Further Information
Publication History
1987
1988
Publication Date:
14 March 2008 (online)

Summary
We explored a 61 year old woman with mild hirsutism. An adrenal tumor was found in the left adrenal, which was held responsible for the androgen secretion. The in vitro incubation of the tumor tissue showed an impaired 11 β-hydroxylation of 11-deoxycortisol. This is a rare and unusual case of adrenal pathology showing that a deficiency in 11 β-hydroxylase activity does not rule out the presence of an adrenocortical adenoma.
Key words
Adrenals - Adrenal Adenoma - Steroidogenesis - 11 β-Hydroxylase Deficiency