Horm Metab Res 1989; 21(6): 320-323
DOI: 10.1055/s-2007-1009225
Clinical

© Georg Thieme Verlag, Stuttgart · New York

Spontaneous Recovery from Hypopituitarism Due to Postpartum Hemorrhage

Takako Ohyama, A. Nagasaka, A. Nakai, T. Aono, Rumi Masunaga, K. Kataoka, Hifumi Nakagawa, S. Kato, T. Kawabe, H. Majima1 , K. Kometani1 , M. Fukushima1
  • Department of Internal Medicine, Fujita-Gakuen Health University School of Medicine, Toyoake, Aichi, Japan
  • 1Department of Gynecology and Obstetrics, Fujita-Gakuen Health University School of Medicine, Toyoake, Aichi, Japan
Further Information

Publication History

1988

1988

Publication Date:
14 March 2008 (online)

Summary

A rare case is presented of a woman with spontaneous recovery from hypopituitarism following postpartum hemorrhage. One month after delivery, serum thyroid hormone, TSH, LH and FSH levels were low, and their secretion from the pituitary gland responded poorly to the TRH and LH-RH tests. Pituitary TSH response was normal 3 months after delivery. In the LH-RH test, pituitary LH and FSH response returned to normal at 2 months. Pituitary GH secretion and serum cortisol levels induced by ITT already responded normally one month postpartum. Excessive secretion of pituitary PRL was observed 3 months after delivery and improved gradually thereafter.

These results indicate that the secretion of pituitary tropic hormones was sensitive to pituitary ischemia in the following order: TSH, gonadotropin, GH and ACTH. The disturbance of these hormones also persisted in the same order.