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Horm Metab Res 1989; 21(10): 558-560
DOI: 10.1055/s-2007-1009287
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© Georg Thieme Verlag, Stuttgart · New York

Changes in the Binding of Angiotensin II to Rat Placental Receptor by Estrogen and Progesterone

O. Kurauchi, S. Mizutani, S. Nomura, M. Furuhashi, M. Kasugai, Y. Tomoda
  • Department of Obstetrics and Gynecology, Nagoya University School of Medicine, Nagoya, Japan
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Publication History

1988

1989

Publication Date:
14 March 2008 (online)

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Summary

The effects of estradiol and progesterone on the binding of rat placental angiotensin II receptors were examined. Sex steroid (progesterone estradiol plus progesterone) decreased the total number of rat placental angiotensin II receptors, while sex steroid (estradiol plus progesterone) increased angiotensin levels. Our present results suggest that sex steroids may play an important role in the control of the number of the angiotensin binding sites during pregnancy.

Key-Words

Angiotensin II Receptors - Rat Placenta - Progesterone - Estradiol