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Horm Metab Res 1989; 21(12): 646-648
DOI: 10.1055/s-2007-1009310
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© Georg Thieme Verlag, Stuttgart · New York

The Effect of Heat-Stable Extract from Bovine Sublingual Salivary Gland on Serum Cholesterol and Triglyceride Levels in Normal and Hypercholesterolemic Rabbits

H. Omidfar1 , Y. Güven2 , H. Öz1
  • 1Department of Biochemistry, Istanbul Medical Faculty, University of Istanbul
  • 2Department of Biochemistry, Faculty of Dentistry, University of Istanbul, Istanbul, Turkey
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Publication History

1988

1989

Publication Date:
14 March 2008 (online)

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Summary

An extract of bovine sublingual glands (SLF3) reduced the serum cholesterol levels of normal rabbits 34.6% and serum triglyceride levels 19.6% when injected intraperitoneally (i. p.) at 20 mg/kg body wt on alternate days for 7 days. SLF3 also reduced serum cholesterol levels 69.0% and triglyceride levels 46.5% in hypercholesterolemic rabbits, while in similar rabbits injected with a control muscle tissue extract, the rate of decrease in serum cholesterol levels was 33.3% and triglyceride levels 26.7%.

Key-Words

Sublingual Salivary Glands - Hypercholesterolemic Rabbits - Lipid Metabolism