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Horm Metab Res 1987; 19(12): 606-608
DOI: 10.1055/s-2007-1011891
DOI: 10.1055/s-2007-1011891
ORIGINALS
Basic
© Georg Thieme Verlag, Stuttgart · New York
Requirement of a Compartmentalization for NADPH Oxidizing Site and Peroxidase-H2O2 in the Thyroid Iodinating System
Weitere Informationen
Publikationsverlauf
1986
1987
Publikationsdatum:
14. März 2008 (online)


Summary
In this study, it is shown that NADPH iodination occurs in a thyroid peroxidase-H2O2 system in presence of thyroglobulin, the normal iodination substrate. Previous data suggested that thyroid H2O2generation is a NADPH-dependent system. Present results support the concept of a Compartmentalization of the sites of NADPH oxidation and peroxidasic iodination.
Key-Words
Thyroid Peroxidase - NADPH - H2O2 Production