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Horm Metab Res 1986; 18(8): 555-557
DOI: 10.1055/s-2007-1012372
Clinical

© Georg Thieme Verlag, Stuttgart · New York

Increased CSF Levels of Somatostatin in Patients with Brain Tumours and Intracranial Hypertension

H. Stępień1 , A. Stawowy2 , D. Cieślak1 , J. Brzeziński2 , M. Pawlikowski1
  • 1Department of Experimental Endocrinology and Hormone Chemistry, Medical Academy of Łódź, Łódź, Poland
  • 2Department of Neurosurgery, Medical Academy of Łódź, Łódź, Poland
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Publication History

1984

1985

Publication Date:
14 March 2008 (online)

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Summary

The cerebrospinal fluid (CSF) levels of somatostatin in patients with brain tumours, communicating hydrocephalus, lumbar-disc disease (treated as a control) were measured by specific radioimmunoassay. The somatostatin concentration in the patients with brain tumours and intracranial hypertension was significantly higher compared to those with brain tumours and normal CSF pressure. CSF somatostatin content in patients with communicating hydrocephalus, was similar to patients with brain tumours and normal CSF pressure, and did not show a significant difference from the control group. The authors discuss possible reasons for such results obtained in patients with brain tumours and intracranial hypertension.

Key-Words

Somatostatin - Brain Tumours - CSF