Development of a Laser Balloon for the Treatment of Gastrointestinal Obstruction

D. Fleischer; E. Cattau Jr; E. Sinofky; J. Newsome; E. Lack; A. Andriuk; S. Benjamin

doi:10.1055/s-2007-1012906

Endoscopy, Inhaltsverzeichnis

Endoscopy 1989; 21(2): 81-85
DOI: 10.1055/s-2007-1012906

Development of a Laser Balloon for the Treatment of Gastrointestinal Obstruction

D. Fleischer, E. Cattau Jr., E. Sinofky, J. Newsome, E. Lack, A. Andriuk, S. Benjamin

Division of Gastroenterology, Department of Pathology, and the Research Resource Facility of Georgetown University School of Medicine, Washington, D.C., and C. R. Bard, Inc., Billerica, MA, USA

Abstract

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Summary

This work describes the initial results using a laser balloon in a canine model in an attempt to deliver the energy in a circumferential pattern. A balloon catheter, 2 cm long and 3 mm in diameter, was developed. Using a standard cw 100 watt Nd:YAG laser, a 600 micron fiber was tapered to 200 microns and passed through the proximal end of the balloon. Laparotomies were performed on mongrel dogs 14-18 kg in weight. After a gastrotomy, the gastric mucosa was exposed and rugal folds were pulled over the balloon to create a cylinder. Using power settings between 10 and 60 watts, and pulse durations between 10 and 40 seconds, radial energy was delivered and the tissue was examined for both gross and histologic effects. Circumferential zones of coagulation and necrosis were demonstrated.

Key words:

GI obstruction - Laser therapy - Canine model - Nd:YAG laser

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