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Thorac Cardiovasc Surg 1985; 33(2): 94-97
DOI: 10.1055/s-2007-1014095
© Georg Thieme Verlag Stuttgart · New York

Changes in Myocardial Oxygen Demand and Instantaneous Ventricular Vascular Volume during Prolonged Cross-clamping and Reperfusion of the Abdominal Aorta

Wang Cheng, Zhang Chong, Liu Rai-Lian, Song Xiang-Ling
  • Department of Cardiothoracic Surgery, No. 3, Clinical College, Bethune Medical University, Changchun, China
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Publication History

1985

Publication Date:
19 March 2008 (online)

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Summary

In 47 animals (rats, rabbits) the cardiac side effects of prolonged (3 to 6 hours) abdominal aortic cross-clamping and unclamping (3 to 6 hours) were investigated. The relative instantaneous ventricular vascular volume (IVVV), a factor reflecting myocardial blood supply and the rate pressure product (RPP) representing myocardial oxygen demand were used as Parameters. Following cross-clamping the IVVV showed an initial decrease while the myocardial oxygen demand revealed a sudden increase. After unclamping, the myocardial oxygen demand decreased and IVVV improved. Minimal levels of both IVVV and RPP occurred at 6 hours following unclamping. This may be an effect of a myocardial inhibiting substance, released by ischemia and necrosis of the lower extremity.

Key words

Abdominal aortic cross-clamping - Myocardial oxygen demand - Instantaneous ventricular vascular volume - Rate pressure product