Endoscopy 1987; 19(6): 221-224
DOI: 10.1055/s-2007-1018288
ORIGINAL CONTRIBUTIONS

© Georg Thieme Verlag KG Stuttgart · New York

N-Butyl-2-Cyanoacrylate: A Supplement to Endoscopic Sclerotherapy

N. Soehendra, H. Grimm, V.Ch. Nam, B. Berger
  • Department of Surgery, University Hospital of Hamburg
Further Information

Publication History

Publication Date:
17 March 2008 (online)

Summary

We report on our two years' experience with the tissue adhesive n-butyl-2-cyanoacrylate. During this period 202 patients suffering from esophagogastric varices were treated endoscopically. With the aid of the tissue adhesive the conventional sclerotherapy with Polidocanol 1 % has been clearly improved. Problems concerning early recurrent bleeding and fundic varices are satisfactorily solved. The endoscopic hemostasis of severe variceal bleedings has become safer and surer. The overall hospital mortality of these patients has sunk from 31.5 to 17.5 %. Cyanoacrylate is a very useful substance for obliterating large esophagogastric varices. However, the complete elimination of esophageal varices, which is the guarantee for a long-term freedom from recurrent bleeding, can only be achieved by using a genuine sclerosing agent.