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Endoscopy 1984; 16(2): 43-46
DOI: 10.1055/s-2007-1018530
Original Contributions

© Georg Thieme Verlag KG Stuttgart · New York

Possible Mechanism of Hemostasis Effected by Electrocoagulation

P. Wara, V. Berg, N.O. Jacobsen, C. Casalnuovo, E. Amdrup
  • Surgical Gastroenterological Department L., and Institute of Pathology, Arhus Kommunehospital, University of Arhus, Arhus, Denmark
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Publication History

Publication Date:
15 April 2008 (online)

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Summary

Forty acute gastric ulcers were created in 10 rabbits. The bleeding was controlled by monopolar electrocoagulation in 20 ulcers, the remaining ulcers were left untreated as controls. Spontaneous intravascular thrombosis was precluded by heparinization. A histological assessment in the acute stage revealed significant morphological alterations in electrocoagulated ulcers, with fibrin deposition, decreased tissue stainability and swelling of the vessel walls, indicating heat-induced damage including cells of the vessel walls. An intravascular occlusive fibrin thrombosis demonstrated in all coagulated ulcers is suggested to be the probable mechanism of hemostasis.

Key words:

Hemostatic effect - Acute gastric ulcers - Electrocoagulation - Heparinization - Fibrin deposition