Incorporation In Vivo of Radioisotopic Precursors into Seromucoid Proteins in Streptozotocin Diabetic Rats

A. Guzdek; J. Noworytko; M. Sarnecka-Keller

doi:10.1055/s-2007-1019314

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Horm Metab Res 1981; 13(9): 491-494
DOI: 10.1055/s-2007-1019314

Incorporation In Vivo of Radioisotopic Precursors into Seromucoid Proteins in Streptozotocin Diabetic Rats

A. Guzdek, J. Noworytko, M. Sarnecka-Keller

Department of Animal Biochemistry, Institute of Molecular Biology, Jagiellonian University, Grodzka, Cracow, Poland

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Publication History

1979

1980

Publication Date:
14 March 2008 (online)

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Summary

In vivo incorporations of ¹⁴C-leucine and ³H-galactose into the seromucoid proteins are decreased in Streptozotocin diabetic rats. The decrease in galactose incorporation is greater than that of leucine, and suggests that Streptozotocin diabetes influences the metabolism of both the protein and sugar moieties of seromucoid glycoproteins.

Key-Words:

Streptozotocin Diabetes - Glycoprotein Biosynthesis - Seromucoid - ¹⁴C-Leucine - ³H-Galactose