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Thorac Cardiovasc Surg 1983; 31(1): 21-25
DOI: 10.1055/s-2007-1020286
Special Article

© Georg Thieme Verlag Stuttgart · New York

Phrenic Nerve Pacing for the Treatment of Central Hypoventilation Syndrome - State of the Art and Case Report

H. Meisner, J. G. Schöber, E. Struck, B. Lipowski1 , P. Mayser2 , F. Sebening
  • German Heart Center, Munich
  • 1Pediatric Outpatient Department, University of Munich
  • 2Municipal Hospital, Munich-Harlaching
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Publication History

Publication Date:
19 March 2008 (online)

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Summary

The application of phrenic nerve pacing is an effective method of respiratory support in adults with certain forms of acquired failure of automatic ventilation. The experience with one infant suffering from congenital central hypoventilation (Ondine's syndrome) is summarized in this report. Stimulation electrodes were implanted on the thoracic portion of each phrenic nerve. After a cumbersome period of intensive medical care and conditioning of the phrenic nerve-diaphragm system, the patient could be weaned off the respirator. Severe upper airway obstruction, however, required tracheostomy. Bilateral simultaneous pacing has been effectíve now for more than 2 years providing the desired normal ventilation during sleep. The state of the art of phrenic nerve pacing is described.

Key words

Ondine's syndrome - Phrenic nerve pacing