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Thorac Cardiovasc Surg 1986; 34(1): 49-51
DOI: 10.1055/s-2007-1020372
DOI: 10.1055/s-2007-1020372
Reduction of Thrombogenicity in Small-diameter Vascular Prostheses Seeded with Autologous Endothelial Cells
Further Information
Publication History
Publication Date:
19 March 2008 (online)
Summary
In a canine model small-diameter vascular grafts of knitted Dacron were seeded with autologous endothelial cells. Four weeks after surgery the grafts were removed. Seeded grafts showed a pseudo-intima covered by a monolayer, whereas control grafts showed a cellular lining only at the anastomoses. Graft pretreatment with either fibrin glue or autologous blood in combination with endothelial cell seeding promoted the neointima formation.
Key words
Vascular prostheses - Endothelial cell seeding - Fibrin glue