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Endoscopy 1981; 13(2): 57-59
DOI: 10.1055/s-2007-1021647
© Georg Thieme Verlag KG Stuttgart · New York

Influence of an Antiarrhythmic Premedication on the Development of Premature Ventricular Contractions During Fiberoptic Gastroduodenoscopy

H. Pristautz, H. Biffl, W. Leitner, P. Parsché, P. Schmid
  • Department of Internal Medicine of the University Clinic of Graz, Austria (Medical Director: Prof. Dr. S. Sailer)
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Publication Date:
17 March 2008 (online)

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Summary

Heart rate, blood pressure and ECG changes during fiberoptic gastroscopy were examined in 128 patients, 60 of whom had been orally premedicated with Mexiletine. 55 % of the non-premedicated patients developed occasional, and 22 % of this group developed accumulated or frequent, premature ventricular contractions. In the patient group with antiarrhythmic premedication, the respective figures were 25 % and 8 %, and in this group patients with a normal ECG developed premature ventricular contractions less frequently than patients with pathological changes in the ST segment. The antiarrhythmic premedication had no influence on pulse or blood pressure.

Key words:

Mexiletine - Gastroscopic examinations - Premature ventricular contractions