Six patients with immunoproliferative small intestinal disease (IPSID), were examined
endoscopically. The disease was found to involve the duodenum and jejunum and was
characterized by the loss of the mucosal circular folds, a thickened cobblestone appearance
of the mucosa and multiple sessile polyps. Ulceration of the mucosa was seen in one
patient. A large ulcerated mass was seen in the third part of the duodenum in one
patient.
Lymphoma - Immunoproliferative disease - Malabsorption syndrome - Heavy chain disease