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Thorac Cardiovasc Surg 1983; 31(3): 185-186
DOI: 10.1055/s-2007-1021976
© Georg Thieme Verlag Stuttgart · New York

Closure of Lung Leaks by Fibrin Gluing. Experimental Investigations and Clinical Experience

R. Türk, J. W. Weidringer, W. Hartel1 , G. Blümel
  • Institute for Experimental Surgery, Technical University, Munich, FRG
  • 1Division of Surgery, Bundeswehrkrankenhaus, Ulm, FRG
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Publication History

Publication Date:
19 March 2008 (online)

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Summary

In 28 male Wistar rats a standardized lung incision was closed by running suture and in half of the animals by additional application of fibrin adhesive. The animals were sacrificed 30 minutes and 5 days postoperatively. A significantly higher tolerance to increased inflation pressure was found in the fibrin-treated group. Ten patients undergoing pulmonary resection had conventional closure of parenchymatous lesions with additional fibrin gluing. Under positive air way pressure ventilation the sealing effect proved to be better after application of fibrin adhesive to the sutured area.

Key words

Fibrin adhesive - Lung sutures - Gas-Ieakage