The Use of Fibrin Glue for Sealing Vascular Prostheses of High Porosity

Summary

Vascular prostheses of different porosity (Cooley Very Soft[1]; Miliknit Lo-Por[2]; Microvel[3]; Sparks Mandril[4]) were pretreated with fibrin glue and the permeability was assessed both in vitro and in 12 dog experiments by descending aorta replacement under full systemic heparinization. It was found that all types of prostheses were completely sealed after the pretreatment.

In 28 patients undergoing descending or abdominal aorta replacement under systemic heparinization high porosity knitted Dacron grafts were pretreated with the fibrin glue only. There was no blood loss across the prosthetic wall. It is concluded that g raft -pretreatment with fibrin glue allows for combining full heparinization and the use of high porosity vascular grafts.

Key Words

Vascular prostheses - Graft porosity - Fibrin glue

1 Braun-Dexon GmbH, D-3509 Spangenberg

2 Golaski Lab. Inc., Philadelphia, Pennsylvania 19144, USA

3 Braun-Dexon GmbH, D-3509 Spangenberg

4 Edwards Lab., Abt. de American Hospital Supply, Deutschland GmbH, Postfach 500449, Lerchenstr. 5, D-8000 München 50

1 Braun-Dexon GmbH, D-3509 Spangenberg

2 Golaski Lab. Inc., Philadelphia, Pennsylvania 19144, USA

3 Braun-Dexon GmbH, D-3509 Spangenberg

4 Edwards Lab., Abt. de American Hospital Supply, Deutschland GmbH, Postfach 500449, Lerchenstr. 5, D-8000 München 50