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DOI: 10.1055/s-2007-962857
© Georg Thieme Verlag KG Stuttgart · New York
Differenzialdiagnose bilateraler Thalamusläsionen
Differential Diagnosis of Bilateral Thalamic LesionsPublication History
eingereicht: 8.9.2006
angenommen: 12.12.2006
Publication Date:
26 February 2007 (online)

Zusammenfassung
Eine Vielzahl unterschiedlicher Erkrankungen kann sich mit bilateralen Thalamusläsionen manifestieren. Dazu gehören einerseits vaskuläre Erkrankungen, die eine möglichst rasche therapeutische Intervention erfordern, wie z. B. die Basilarisspitzenembolie und die innere Hirnvenenthrombose, sowie andererseits auch Tumoren, infektiöse oder demyelinisierende Erkrankungen sowie metabolisch-toxische Veränderungen. Eine detaillierte Kenntnis der typischen bildgebenden Befunde der verschiedenen Krankheitsbilder ist daher für eine aussagekräftige radiologische Diagnose unerlässlich. Die vorliegende Arbeit gibt einen Überblick über die radiologischen Befunde der wichtigsten bithalamischen Erkrankungen und liefert eine aktuelle Literaturübersicht zu diesem Thema.
Abstract
A multitude of different diseases can result in bilateral thalamic lesions. These include vascular pathologies requiring prompt therapeutic intervention, such as basilar thrombosis or thrombosis of the internal cerebral veins, as well as tumors, infectious or demyelinating diseases, and toxic-metabolic lesions. Therefore, detailed knowledge of the typical radiological findings for the various diseases is essential for determining the correct diagnosis. This review provides a synopsis of the radiological findings for the most important bithalamic lesions and an overview of the literature.
Key words
thalamus - bilateral lesions - MRI
Literatur
- 1 Danek A. Sonderfall bilateral-symmetrische Infarkte. Hamann GF, Siebler M, von Scheidt W Schlaganfall Landsberg; ecomed 2002: 189-198
MissingFormLabel
- 2
Schmahmann J D.
Vascular syndromes of the thalamus.
Stroke.
2003;
34
2264-2278
MissingFormLabel
- 3
Weidauer S, Nichtweiß M, Zanella F E. et al .
Assessment of paramedian thalamic infarcts: MR imaging, clinical features and prognosis.
Eur Radiol.
2004;
14
1615-1626
MissingFormLabel
- 4
Tatu L, Moulin T, Bogousslavsky J. et al .
Arterial territories of the human brain: Cerebral hemispheres.
Neurology.
1998;
50
1699-1708
MissingFormLabel
- 5
Bogousslavsky J, Regli F, Assal G.
The syndrome of unilateral tuberothalamic artery territory infarction.
Stroke.
1986;
17
434-441
MissingFormLabel
- 6
Percheron G.
Arteries of the human thalamus. II. Arteries and paramedian thalamic territory of
the communicating basilar artery.
Rev Neurol (Paris).
1976;
132
309-324
MissingFormLabel
- 7
Caplan L R.
„Top of the basilar” syndrome.
Neurology.
1980;
30
72-79
MissingFormLabel
- 8
Roitberg B Z, Tuccar E, Alp M S.
Bilateral paramedian thalamic infarct in the presence of an unpaired thalamic perforating
artery.
Acta Neurochir (Wien).
2002;
144
301-304
MissingFormLabel
- 9
Chan S, Kartha K, Yoon S S. et al .
Multifocal hypointense cerebral lesions on gradient-echo MR are associated with chronic
hypertension.
AJNR Am J Neuroradiol.
1996;
17
1821-1827
MissingFormLabel
- 10
Imaizumi T, Horita Y, Chiba M. et al .
Dot-like hemosiderin spots on gradient echo T2*-weighted magnetic resonance imaging
are associated with past history of small vessel disease in patients with intracerebral
hemorrhage.
J Neuroimaging.
2004;
14
251-257
MissingFormLabel
- 11
Liebetrau M, Mayer T E, Brüning R. et al .
Intra-arterial thrombolysis of complete deep cerebral venous thrombosis.
Neurology.
2004;
63
2444-2445
MissingFormLabel
- 12
Peeters E, Stadnik T, Bissay F. et al .
Diffusion weighted MR imaging of an acute venous stroke: case report.
AJNR Am J Neuroradiol.
2001;
22
1949-1952
MissingFormLabel
- 13
Ducreux D, Oppenheim C, Vandamme X. et al .
Diffusion-weighted imaging patterns of brain damage associated with cerebral venous
thrombosis.
AJNR Am J Neuroradiol.
2001;
22
261-268
MissingFormLabel
- 14
Greenough G P, Mamourian A, Harbaugh R E.
Venous hypertension associated with a posterior fossa dural arteriovenous fistula:
another cause of bithalamic lesions on MR images.
AJNR Am J Neuroradiol.
1999;
20
145-147
MissingFormLabel
- 15
Tanaka K, Marooka Y, Nakagawa Y. et al .
Dural arteriovenous malformation manifesting as dementia due to ischemia in bilateral
thalami. A case report.
Surg Neurol.
1999;
51
489-493
MissingFormLabel
- 16
Tihan T, Burger P C, Pomper M. et al .
Subacute diencephalic angioencephalopathy: biopsy diagnosis and radiological features
of a rare entity.
Clin Neurol Neurosurg.
2001;
103
160-167
MissingFormLabel
- 17
Cheek W R, Taveras J M.
Thalamic tumors.
J Neurosurg.
1966;
24
505-513
MissingFormLabel
- 18
Partlow G D, del Carpio O DR, Melanson D. et al .
Bilateral thalamic glioma: review of eight cases with personality change and mental
detoriation.
AJNR Am J Neuroradiol.
1992;
13
1225-1230
MissingFormLabel
- 19
Estève F, Grand S, Rubin C. et al .
MR spectroscopy of bilateral thalamic gliomas.
AJNR Am J Neuroradiol.
1999;
20
876-881
MissingFormLabel
- 20
Hirano H, Yokoyama S, Nakayama M. et al .
Bilateral thalamic glioma: case report.
Neuroradiology.
2000;
42
732-734
MissingFormLabel
- 21
Lichy M P, Bachert P, Hamprecht F. et al .
Einsatz der 1H-MR-spektroskopischen Bildgebung in der Strahlentherapie: Cholin als Marker für die
Bestimmung der relativen Wahrscheinlichkeit eines Tumorprogresses nach Bestrahlung
glialer Hirntumoren.
Fortschr Röntgenstr.
2006;
178
627-633
MissingFormLabel
- 22
Erdogan C, Hakyemez B, Yildirim N. et al .
Brain abscess and cystic brain tumor: discrimination with dynamic susceptibility contrast
perfusion-weighted MRI.
J Compu Assist Tomogr.
2005;
29
663-667
MissingFormLabel
- 23
Di Costanzo A, Scarabino T, Trojsi F. et al .
Multiparametric 3T MR approach to the assessment of cerebral gliomas: tumor extent
and malignancy.
Neuroradiology.
2006;
48
622-631
MissingFormLabel
- 24
Smyth E G, Stern K.
Tumors of the thalamus: a clinico-pathological study.
Brain.
1938;
61
339-374
MissingFormLabel
- 25
Burger P C, Cohan P C, Rosenblum M K. et al .
Pathology of diencephalic astrocytomas.
Pediatr Neurosurg.
2000;
32
214-219
MissingFormLabel
- 26
Rauscher A, Sedlacik J, Fitzek C. et al .
Bestimmung des Einflusses eines gasförmigen Kontrastmittels auf zerebrale Tumoren
mittels hochaufgelöster suszeptibilitätsgewichteter MR-Bildgebung.
Fortschr Röntgenstr.
2005;
177
1065-1069
MissingFormLabel
- 27
Kim D I, Yoon P H, Ryu Y H. et al .
MRI of germinomas arising from the basal ganglia and thalamus.
Neuroradiology.
1998;
40
507-511
MissingFormLabel
- 28
Kalita J, Misra U K.
Comparison of CT scan and MRI findings in the diagnosis of Japanese encephalitis.
J Neurol Sci.
2000;
174
3-8
MissingFormLabel
- 29
Petropoulou K A, Gordon S M, Prayson R A. et al .
West Nile virus meningo-encephalitis: MR imaging findings.
AJNR Am J Neuroradiol.
2005;
26
1986-1995
MissingFormLabel
- 30
Deresiewicz R L, Thaler S J, Shu L. et al .
Clinical and neuroradiographic manifestations of Eastern equine encephalitis.
N Engl J Med.
1997;
336
1867-1874
MissingFormLabel
- 31
Johkura K, Momoo T, Kuroiwa Y.
Thalamic involvement of Epstein-Barr virus encephalitis demonstrated by MRI.
J Neurol.
2003;
250
357-358
MissingFormLabel
- 32
Schankin C J, Birnbaum T, Linn J. et al .
A fatal encephalitis.
Lancet.
2005;
365
358
MissingFormLabel
- 33
Hähnel S, Storch-Hagenlocher B, Kress B. et al .
Infektiöse Erkrankungen des Hirnparenchyms bei Erwachsenen: Bildgebung und differenzialdiagnostische
Aspekte.
Fortschr Röntgenstr.
2005;
177
1349-1365
MissingFormLabel
- 34
Vercellino M, Plano F, Votta B. et al .
Grey matter pathology in multiple sclerosis.
J Neuropathol Exp Neurol.
2005;
64
1101-1107
MissingFormLabel
- 35
Garg R K.
Acute disseminated encephalomyelitis.
Postgrad med J.
2003;
79
11-17
MissingFormLabel
- 36
Prayer L, Wimberger D, Kramer J. et al .
Cranial MRI in Wilson’s disease.
Neuroradiology.
1990;
32
211-214
MissingFormLabel
- 37
King A D, Walshe J M, Kendall B E. et al .
Cranial MR imaging in Wilson’s disease.
AJR Am J Roentgenol.
1996;
167
1579-1584
MissingFormLabel
- 38
Sener R N.
Diffusion MR imaging changes associated with Wilson disease.
AJNR Am J Neuroradiol.
2003;
24
965-967
MissingFormLabel
- 39
Vymazal J, Babis M, Brooks R A. et al .
T1 and T2 alterations in the brains of patients with hepatic cirrhosis.
AJNR Am J Neuroradiol.
1996;
17
333-336
MissingFormLabel
- 40
Zeidler M, Sellar R J, Collie D A. et al .
The pulvinar sign on magnetic resonance imaging in variant Creutzfeldt-Jakob disease.
Lancet.
2000;
355
1412-1418
MissingFormLabel
- 41
Collie D A, Summers D M, Sellar R J. et al .
Diagnosing variant Creutzfeldt-Jakob disease with the pulvinar sign: MR imaging findings
in 86 neuropathologically confirmed cases.
AJNR Am J Neuroradiol.
2003;
24
1560-1569
MissingFormLabel
- 42
Kallenberg K, Schulz-Schaeffer W J, Jastrow U. et al .
Creutzfeldt-Jakob disease: comparative analysis of MR imaging sequences.
AJNR Am J Neuroradiol.
2006;
27
1459-1462
MissingFormLabel
- 43
Ukisu R, Kushihashi T, Kitanosono T. et al .
Serial diffusion-weighted MRI of Creutzfeldt-Jakob disease.
AJR Am J Roentgenol.
2005;
184
560-566
MissingFormLabel
- 44
Mittal S, Farmer P, Kalina P. et al .
Correlation of diffusion-weighted magnetic resonance imaging with neuropathology in
Creutzfeldt-Jakob disease.
Arch Neurol.
2002;
59
128-134
MissingFormLabel
- 45
Haik S, Dormont D, Faucheux B A. et al .
Prion protein deposits match magnetic resonance imaging signal abnormalities in Creutzfeldt-Jakob
disease.
Ann Neurol.
2002;
51
797-799
MissingFormLabel
- 46
White M L, Zhang Y, Andrew L G. et al .
MR imaging with diffusion-weighted imaging in acute and chronic Wernicke encephalopathy.
AJNR Am J Neuroradiol.
2005;
26
2306-2310
MissingFormLabel
- 47
Chu K, Kang D W, Kim H J. et al .
Diffusion-weighted imaging abnormalities in Wernicke encephalopathy: reversible cytotoxic
edema?.
Arch Neurol.
2002;
59
123-127
MissingFormLabel
- 48
Koci T M, Chiang F, Chow P. et al .
Thalamic extrapontine lesions in central pontine myelinolysis.
AJNR Am J Neuroradiol.
1990;
11
1229-1233
MissingFormLabel
- 49
Cramer S C, Stegbauer K C, Schneider A. et al .
Decreased diffusion in central pontine myelinolysis.
AJNR Am J Neuroradiol.
2001;
22
1476-1479
MissingFormLabel
Dr. Jennifer Linn
Abteilung für Neuroradiologie Universitätsklinikum München
Marchioninistrasse 15
81377 München
Phone: ++49/89/70 95 32 61
Fax: ++49/89/70 95 25 09
Email: linn@nrad.de