Relationship between Muscle Oxygenation Kinetics and the Rate of Decline in Peak Torque during Isokinetic Knee Extension in Acute Hypoxia and Normoxia

Abstract

To investigate whether low FiO₂ affects muscle oxygenation and the rate of decline in peak torque (DR) during isokinetic knee extension, subjects performed 50 isokinetic knee extensions at 180°/s and at 0.5 Hz while inhaling low O₂ gas (12 %O₂; H) or air (N). Muscle oxygenation kinetics was assessed by near-infrared spectroscopy, and whole-body V·O₂ and HR were measured. We calculated total-, oxy- and deoxy-hemoglobin/myoglobin concentrations (TotalHb/Mb, OxyHb/Mb, DeoxyHb/Mb), and the slopes of the change in OxyHb/Mb during exercise. SpO₂ decreased in H while DR and V·O₂ did not differ between the conditions. During exercise, OxyHb/Mb was lower in H than in N, and DeoxyHb/Mb was higher in H than in N. TotalHb/Mb began to increase from the resting level earlier in H. HR was higher during the latter half of the exercise in H. The slopes of the change in OxyHb/Mb were the same in the two conditions. Our results show that low FiO₂ decreases SpO₂ and muscle oxygenation during maximal isokinetic knee extension. However, low SpO₂ and muscle oxygenation did not affect the rates of decline of peak torque. These results suggest that the decline in peak torque occurs for reasons other than O₂ availability.

Key words

near‐infrared spectroscopy - oxygenation - isokinetic knee extension - hypoxia

References

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