A Novel and Efficient Synthesis of Unsymmetrical Disulfides

Sylwia Antoniow; Dariusz Witt

doi:10.1055/s-2007-965873

PAPER

A Novel and Efficient Synthesis of Unsymmetrical Disulfides

Sylwia Antoniow, Dariusz Witt*
Department of Organic Chemistry, Chemical Faculty, Gdansk University of Technology, Narutowicza 11/12, 80-952 Gdansk, Poland
Fax: +48(58)3472694; e-Mail: dwitt@chem.pg.gda.pl;

Abstract

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Abstract

Unsymmetrical disulfides have been prepared from the corresponding thiols and bis-(5,5-dimethyl-2-thiono-1,3,2-dioxaphosphorinanyl)disulfide under mild conditions with good to excellent yields. The method can be applied to thiols bearing neutral, aromatic, basic or acidic functionalities with variable length of carbon chain.

Key words

unsymmetrical disulfides - alkanethiols - l-cysteine - thiophenol

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