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Synthesis 2007(7): 1015-1020
DOI: 10.1055/s-2007-965946
DOI: 10.1055/s-2007-965946
PAPER
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Novel 1,2,3,4-Tetrahydroisoquinoline-3-carboxylic Acid Derivatives through the Application of Rongalite: A Synergistic Combination of [2+2+2]- and [4+2]-Cycloaddition Reactions
Weitere Informationen
Received
5 January 2007
Publikationsdatum:
20. Februar 2007 (online)
Publikationsverlauf
Publikationsdatum:
20. Februar 2007 (online)
![](https://www.thieme-connect.de/media/synthesis/200707/lookinside/thumbnails/10.1055-s-2007-965946-1.jpg)
Abstract
An efficient route for the synthesis of several novel 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) derivatives has been reported. A synergistic combination of [2+2+2]- and [4+2]-cycloaddition reactions has been used for the synthesis of the desired targets.
Key words
1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid - Rongalite - cycloaddition - amino acids - quinones
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