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Synthesis 2007(8): 1214-1224
DOI: 10.1055/s-2007-966003
DOI: 10.1055/s-2007-966003
PAPER
© Georg Thieme Verlag Stuttgart · New York
Chlorotrimethylsilane-Mediated Friedländer Synthesis of Polysubstituted Quinolines
Weitere Informationen
Received
12 December 2006
Publikationsdatum:
28. März 2007 (online)
Publikationsverlauf
Publikationsdatum:
28. März 2007 (online)
Abstract
New convenient conditions for the Friedländer synthesis of quinolines are described. Polysubstituted quinolines were readily prepared using chlorotrimethylsilane as a promoter and water-acceptor agent.
Key words
quinolines - annulation - o-amino aromatic carbonyls - chlorotrimethylsilane - parallel synthesis
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