Abstract
Synthesis of a racemic 4′-ethynyl-2′-deoxyribose intermediate using stereoselective chelation control is presented. This intermediate is further transformed to 4′-ethynyl-2′-deoxy- and 4′-ethynyl-2′,3′-dideoxy-2′,3′-didehydronucleoside analogues.
Key words
HIV - nucleosides - stereoselective synthesis - carbohydrates - chelation control
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