Endoscopy 2007; 39(11): 1018-1020
DOI: 10.1055/s-2007-966783
Case report

© Georg Thieme Verlag KG Stuttgart · New York

Confocal laser endomicroscopy in celiac disease: description of findings in two cases

A.  Zambelli1 , V.  Villanacci2 , E.  Buscarini1 , G.  Lupinacci1 , F.  De Grazia1 , G.  Brambilla1 , F.  Menozzi1 , L.  La Mantia1 , G.  Bassotti3
  • 1Gastroenterology and Endoscopy Unit, Maggiore Hospital, Crema, Italy
  • 22nd Pathology Department, Spedali Civili, Brescia, Italy
  • 3Gastroenterology and Hepatology Section, Department of Clinical and Experimental Medicine, University of Perugia, Italy
Weitere Informationen

Publikationsverlauf

submitted 22 February 2007

accepted after revision 14 June 2007

Publikationsdatum:
10. Oktober 2007 (online)

Preview

Duodenal confocal laser endomicroscopy (CLE) was carried out in six patients to compare the findings with histology. The visibility and quality of the endomicroscopy images were quantified using the following score: 0 = none; 1 = poor; 2 = fair; 3 = good. Four patients had a normal duodenal mucosa, whereas two patients in whom CLE indicated villous atrophy showed histologic features typical of celiac disease. Histology and CLE images were similar in both normal and celiac disease patients; patients with celiac disease had an average score of 3 for epithelial architecture, 3 for goblet cells, 3 for vessels, 1 for inflammatory infiltrate, and 2 for crypt visibility.

References

A. Zambelli, MD

Gastroenterology and Endoscopy Unit

Maggiore Hospital

Largo Dossena 2

26013 Crema

Italy

Fax: +39-0373-280654

eMail: a.zambelli@hcrema.it