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DOI: 10.1055/s-2007-967092
© J. A. Barth Verlag in Georg Thieme Verlag KG · Stuttgart · New York
An Unusual Cause of Severe Hypoglycaemia in Type 1 Diabetes Mellitus. Antepartum Pituitary Failure: A Case Report and Literature Review
Publication History
received 1. 11. 2005
first decision 20. 12. 2005
accepted 28. 12. 2005
Publication Date:
22 February 2007 (online)


Abstract
We describe an unusual cause of severe hypoglycaemia, secondary to hypopituitarism as a result of antepartum pituitary failure, in a pregnant patient with type 1 diabetes mellitus (T1DM). Antepartum pituitary failure is a very rare condition, which has been reported only in a very small number of pregnant patients with diabetes and presents with an acute onset headache and a sub-arachnoid haemorrhage-like picture. It is a potentially fatal condition to the mother and the child if not recognised and treated. Our case report highlights the importance of thinking about hypopituitarism, as a cause of recurrent hypoglycaemia in pregnant patients with T1DM as missing the diagnosis could be fatal to the mother and child.
Key words
hypopituitarism - diabetes - glucocorticoids