Exp Clin Endocrinol Diabetes 2007; 115(2): 136-138
DOI: 10.1055/s-2007-967092
Case Report

© J. A. Barth Verlag in Georg Thieme Verlag KG · Stuttgart · New York

An Unusual Cause of Severe Hypoglycaemia in Type 1 Diabetes Mellitus. Antepartum Pituitary Failure: A Case Report and Literature Review

A. A. Tahrani 1 , T. E. T. West 1 , A. F. Macleod 1
  • 1Department of Diabetes and Endocrinology, The Hummingbird Centre, Royal Shrewsbury Hospital, Shrewsbury, UK
Further Information

Publication History

received 1. 11. 2005 first decision 20. 12. 2005

accepted 28. 12. 2005

Publication Date:
22 February 2007 (online)

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Abstract

We describe an unusual cause of severe hypoglycaemia, secondary to hypopituitarism as a result of antepartum pituitary failure, in a pregnant patient with type 1 diabetes mellitus (T1DM). Antepartum pituitary failure is a very rare condition, which has been reported only in a very small number of pregnant patients with diabetes and presents with an acute onset headache and a sub-arachnoid haemorrhage-like picture. It is a potentially fatal condition to the mother and the child if not recognised and treated. Our case report highlights the importance of thinking about hypopituitarism, as a cause of recurrent hypoglycaemia in pregnant patients with T1DM as missing the diagnosis could be fatal to the mother and child.