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DOI: 10.1055/s-2007-967165
© Georg Thieme Verlag KG Stuttgart · New York
Tarennane and Tarennone, Two Novel Chalcone Constituents from Tarenna attenuata
Publikationsverlauf
Received: December 6, 2006
Revised: January 15, 2007
Accepted: February 21, 2007
Publikationsdatum:
04. April 2007 (online)
Abstract
Two novel chalcone constituents, tarennane (1) and tarennone (2), together with nine known compounds, were isolated from the whole plant of Tarenna attenuata. By analysis of physical and spectroscopic data, the structures of new compounds were elucidated as (E)-4-[3-(4-hydroxy-3-methoxyphenyl)-acryl]-3,4,5-trimethoxycyclohexa-2,5-dienone (1) and 1,2-bis(3,5-dimethoxy-4-hydroxyphenyl)-3-hydroxypropan-1-one (2). These two compounds were tested for antioxidant activities in the MTT and DPPH assays. Compound 1 revealed potent antioxidant activities against H2O2-induced impairment in PC12 cells, but neither of them showed DPPH radical-scavenging activity with IC50 values of 181.1 and 210.3 μM, respectively.
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Prof. Dr. Xiao-Jiang Hao
Key Laboratory of Phytochemistry and Plant Resources in West China
Kunming Institute of Botany
Chinese Academy of Sciences
Kunming 650204
People’s Republic of China
Telefon: +86-871-522-3263
Fax: +86-871-521-9684
eMail: haoxj@mail.kib.ac.cn
- www.thieme-connect.de/ejournals/toc/plantamedica