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DOI: 10.1055/s-2007-967170
© Georg Thieme Verlag KG Stuttgart · New York
Diterpenoids from Turraeanthus mannii
Publication History
Received: November 23, 2006
Revised: February 12, 2007
Accepted: February 23, 2007
Publication Date:
04 April 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/200705/lookinside/thumbnails/10.1055-s-2007-967170-1.jpg)
Abstract
Three new compounds, 15-acetoxy-12-hydroxy-16-methyl-labda-8(17),13E-diene (1), ent-labda-8(17),13-dien-15,16-olid-19-oic acid methyl ester (2), and 12-hydroxy-labda-8(17),13-dien-15,16-olide (3), together with two known compounds, 19-acetoxy-ent-labda-8(17),13-dien-15,16-olide (4), and 16-acetoxy-12,15-epoxy-15ß-hydroxy-labda-8(17),13(16)-diene (5) were isolated from the stem bark of Turraeanthus mannii (Meliaceae). The structures of compounds 1 - 3 were elucidated by analysis of the spectroscopic data. The crude methanol extract and compound 5 exhibited weak antibacterial and antifungal activity.
Key words
Turraeanthus mannii - Meliaceae - antibacterial activity - antifungal activity - diterpenes - labdanes
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Juliette Catherine Vardamides
Department of Organic Chemistry
University of Douala
P.O. Box 24157
Douala
Cameroon
Phone: +237-791-9603
Fax: +237-340-7569
Email: jucthmas@yahoo.fr