Indole Alkaloids from Tabernaemontana elegans1

R. van der Heijden; R. L. Brouwer; R. Verpoorte; T. A. van Beek; P. A. A. Harkes; A. Baerheim Svendsen

doi:10.1055/s-2007-969101

Planta Medica, Inhaltsverzeichnis

Planta Med 1986; 52(2): 144-147
DOI: 10.1055/s-2007-969101

Full Papers

Indole Alkaloids from Tabernaemontana elegans ¹

R. van der Heijden² , R. L. Brouwer² , R. Verpoorte² , T. A. van Beek⁴ , P. A. A. Harkes³ , A. Baerheim Svendsen²

²Center for Bio-Pharmaceutical Sciences, Division of Pharmacognosy, State University of Leiden, P. O. Box 9502, 2300 RA Leiden, The Netherlands
³Division of Plant Molecular Biology, Subfaculty of Biology, State University of Leiden, Nonnensteeg 3, 2311 VJ Leiden, The Netherlands
⁴Laboratory of Organic Chemistry, Agricultural University, De Dreijen 5, 6703 BC Wageningen, The Netherlands

1 Part 16 in the series “Pharmacognostical studies of Tabernaemontana species”. For part 15 see (1).

Abstract

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Abstract

The isolation of 18 indole alkaloids from a whole plant extract of Tabernaemontana elegans is described. Five new and 13 known alkaloids were isolated and identified. The five new alkaloids are tabernaemontaninol, dregaminol, dregaminol-methylether, 3-R/S-hydroxy-tabernaelegantine B and 3-methoxy-tabernaelegantine C. The other alkaloids are apparicine, 16-S-hydroxy-16, 22-dihydro-apparicine, tubotaiwine, vobasine, vobasinol, dregamine, tabernaemontanine, iso-voacangine, 3-R/S-hydroxy-conodurine, tabernaelegantine A, B, C and D.

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Indole Alkaloids from Tabernaemontana elegans 1

Indole Alkaloids from Tabernaemontana elegans ¹