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Planta Med 1985; 51(2): 169-170
DOI: 10.1055/s-2007-969441
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© Georg Thieme Verlag Stuttgart · New York

Isolation and Structure Determination of Daigremontianin, a Novel Bufadienolide from Kalanchoe daigremontiana

Hildebert Wagner, Manfred Fischer, Hermann Lotter
  • Institute of Pharmaceutical Biology, University of Munich, Karlstraße 27, D-8000 München 2
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1984

1984

Publikationsdatum:
26. Februar 2007 (online)

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Abstract

Two toxic principles of Kalanchoe daigremontiana were isolated and structurally elucidated as bufadienolides with an unusual substitution pattern. Daigremontianin, a novel compound, and bersaldegenin-1,3,5-orthoacetate which was also found in Kalanchoe tubiflora Hamet, show a pronounced sedative, positive inotropic and CNS-activity.