Yuehchukene, a Novel Anti-implantation Indole Alkaloid from Murraya paniculata

Y. C. Kong; K. H. Ng; K. H. Wat; A. Wong; I. F. Saxena; K. F. Cheng; P. P. H. But; H. T. Chang

doi:10.1055/s-2007-969497

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Planta Med 1985; 51(4): 304-307
DOI: 10.1055/s-2007-969497

Research Articles

Yuehchukene, a Novel Anti-implantation Indole Alkaloid from Murraya paniculata

Y. C. Kong¹ , K. H. Ng¹ , K. H. Wat¹ , A. Wong¹ ^, ² , I. F. Saxena¹ ^, ³ , K. F. Cheng⁴ , P. P. H. But¹ , H. T. Chang⁵

¹The Chinese University of Hong Kong, Shatin, N. T., Hong Kong
²Smith Kline & French Laboratory, 709 Swedeland Road, Swedeland, PA 19479, USA
³EG & Mason Research Institute, 57 Union Street, Orcester, MA 01608, USA
⁴The University of Hong Kong, Pokfulam Road, Hong Kong
⁵Zhong Shan University, Guangzhou, China

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Publication History

1985

1985

Publication Date:
26 February 2007 (online)

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Abstract

Yuehchukene, 11β-(3′-indolyl-7,9α,9β-trimethyl-5β,8,9,10β-tetrahydroindano-[2,3-b]indole, a novel dimeric indole alkaloid from the roots of Murray a paniculata has potent anti-implantation activity in rats at 3 mg/kg p. o. dosing on pregnancy day 2.