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Planta Med 1985; 51(6): 498-500
DOI: 10.1055/s-2007-969574
Research Articles

© Georg Thieme Verlag Stuttgart · New York

Pharmacological Study of Uzarigenin-Glucoside-Canaroside

E. Navarro1 , J. Boada1 , R. Rodriguez1 , P. Martin2 , J. Breton3 , A. G. Gonzalez3
  • 1Departamento de Farmacología. Facultad de Medicina. Universidad de La Laguna, Apartado 55, La Cuesta, Tenerife, Spain.
  • 2Departamento de Bioquímica, Facultad de Medicina, Universidad de La Laguna, Tenerife, Spain.
  • 3Instituto de Productos Naturales Orgánicos, CSIC, La Laguna, Tenerife, Spain.
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Publication History

1985

1985

Publication Date:
26 February 2007 (online)

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Abstract

Uzarigenin-glucoside-canaroside (UGC) is a steroid glycoside isolated from the leaves of Isoplexis chalcantha whose pharmacological properties have not been so far studied. In this paper the effect of UGC on isolated auricle of rabbits, urinary excretion of rats, isolated jejunum of rabbits, 86Rb+ uptake by erythrocytes as well as its emetic effect in pigeons are presented, using digoxin as standard. The pharmacological activity of UGC was similar to that of digoxin, UGC possessing, however, a lesser vomiting action.