New Furoacridone Alkaloids from Tissue Culture of Ruta graveolens

A. Nahrstedt; V. Wray; B. Engel; E. Reinhard

doi:10.1055/s-2007-969580

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Planta Med 1985; 51(6): 517-519
DOI: 10.1055/s-2007-969580

Reports

New Furoacridone Alkaloids from Tissue Culture of Ruta graveolens

A. Nahrstedt¹ , V. Wray² , B. Engel³ , E. Reinhard³

¹Institut für Pharmazeutische Biologie der Techn. Universität, Mendelssohnstr. 1, D-3300 Braunschweig, FRG
²Gesellschaft für Biotechnologische Forschung mbH, Mascheroder Weg 1, D-3300 Braunschweig, FRG
³Lehrstuhl für Pharmazeutische Biologie der Universität, Auf der Morgenstelle 8, D-7400 Tübingen, FRG

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Publication History

1985

1985

Publication Date:
26 February 2007 (online)

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Abstract

Two new furacridone alkaloids have been obtained from tissue culture of Ruta graveolens by DCCC of a crude dichloromethane extract and subsequent CC and TLC. On the basis of spectroscopic data their structures have been determined to be 1-hydroxyrutacridone epoxide (3) and its intramolecular substitution product (5, rutagravin); a third furoacridone has been identified as gravacridonol (4).