Biosynthese von Herzglykosiden: Nachweis von nukleotidgebundenen 2,6-Didesoxy-3-O-Methylhexosen in Blättern von Nerium oleander

P. Bauer; B. Kopp; G. Franz

doi:10.1055/s-2007-969607

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Planta Med 1984; 50(1): 12-14
DOI: 10.1055/s-2007-969607

Research Articles

Biosynthese von Herzglykosiden: Nachweis von nukleotidgebundenen 2,6-Didesoxy-3-O-Methylhexosen in Blättern von Nerium oleander

Biosynthesis of cardiac glycosides: Nucleotide-bound 2,6-dideoxy-3-O-methylhexoses in leaf extracts of Nerium oleanderP. Bauer¹ , B. Kopp² , G. Franz¹

¹Lehrstuhl für Pharmazeutische Biologie der Universität, D-8400 Regensburg
²Institut für Pharmakognosie der Universität, Wien, Österreich

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Publication Date:
26 February 2007 (online)

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Abstract

From the leaves of Nerium oleander L. (Apocynaceae) nucleotide bound D-sarmentose and D-diginose were isolated and purified by use of PVP- and charcoal treatment and further separated by paper chromatography and electrophoresis. D-sarmentose and D-diginose werde identified by repeated thinlayer co-chromatography in two different solvent systems. Complete separation of L-oleandrose, D-cymarose, D-sarmentose, D-diginose and D-digitoxose was achieved for the first time with one single TLC-system.