PDF herunterladen
Planta Med 1984; 50(3): 272-274
DOI: 10.1055/s-2007-969700
Reports

© Georg Thieme Verlag Stuttgart · New York

Inhibition of Monoamine Oxidase by Hypercin

O. Suzuki1 , Y. Katsumata2 , M. Oya2 , S. Bladt3 , H. Wagner3
  • 1Department of Legal Medicine, 3600 Handa-cho Hamamatsu University School of Medicine, Hamamatsu 4-31-31, Japan
  • 2Department of Legal Medicine, Nagoya University School of Medicine, Nagoya, Japan
  • 3Institut für Pharmazeutische Biologie der Universität München, Karlstr. 29, D-8000 Müchen 2
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
26. Februar 2007 (online)

Auch verfügbar auf
  als PDF herunterladen  Lizenzen und Reprints

Abstract

Hypericin from Hypericum perforatum was found to inhibit in vitro type A and B monoamine oxidase (MAO's) prepared by treating rat brain mitochondria with selective inhibitors. The inhibition of type A MAO by hypericin was higher than that of type B MAO. The inhibition was almost irreversible for both MAO types.