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Planta Med 1984; 50(3): 272-274
DOI: 10.1055/s-2007-969700
DOI: 10.1055/s-2007-969700
Reports
© Georg Thieme Verlag Stuttgart · New York
Inhibition of Monoamine Oxidase by Hypercin
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Publikationsverlauf
Publikationsdatum:
26. Februar 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/198403/lookinside/thumbnails/10.1055-s-2007-969700-1.jpg)
Abstract
Hypericin from Hypericum perforatum was found to inhibit in vitro type A and B monoamine oxidase (MAO's) prepared by treating rat brain mitochondria with selective inhibitors. The inhibition of type A MAO by hypericin was higher than that of type B MAO. The inhibition was almost irreversible for both MAO types.