Partial Structure of Panaxan A, A Hypoglycaemic Glycan of Panax ginseng Roots1

Masashi Tomoda; Kazuyo Shimada; Chohachi Konno; Kazuhiko Sugiyama; Hiroshi Hikino

doi:10.1055/s-2007-969758

Planta Medica, Inhaltsverzeichnis

Planta Med 1984; 50(5): 436-438
DOI: 10.1055/s-2007-969758

Reports

Partial Structure of Panaxan A, A Hypoglycaemic Glycan of Panax ginseng Roots¹

Masashi Tomoda² , Kazuyo Shimada² , Chohachi Konno³ , Kazuhiko Sugiyama³ , Hiroshi Hikino³

²Kyoritsu College of Pharmacy, Shibakoen, Minato-ku, Tokyo, Japan
³Pharmaceutical Institute, Tohoku University, Aoba-yama, Sendai, Japan

1 Antidiabetes drugs, Part 2. Also Part 71 in the Tohoku University series on the validity of the Oriental medicines

Abstract

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Abstract

A hypoglycaemic constituent, panaxan A, isolated from the roots of Panax ginseng, was revealed to be a glycan with molecular weight of ca. 14000. Spectroscopic and degradative studies demonstrated that panaxan A is mainly composed of α - 1 →; 6 linked D-glucopyranose residues having branching at the C-3 position, the ratio of terminals, branching positions and intermediate units being ca. 1:1:2.

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