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DOI: 10.1055/s-2007-969870
© Hippokrates Verlag Stuttgart
Biotransformation of Cannabidiol to Cannabielsoin by Suspension Cultures of Cannabis sativa and Saccharum officinarum
Publication History
1982
1982
Publication Date:
26 March 2007 (online)
![](https://www.thieme-connect.de/media/plantamedica/198305/lookinside/thumbnails/10.1055-s-2007-969870-1.jpg)
Abstract
Suspension cultures of Cannabis sativa L. and Saccharum officinarum L. have been shown to biotransform cannabidiol to Cannabielsoin under normal growth conditions. Both Cannabielsoin C-1 stereoisomers were produced. Mass spectral and chromatographic evidence were used in this identification. This is the first reported biologically catalyzed synthesis of Cannabielsoin as well as the first biotransformation of any cannabinoid by plant tissue culture systems. Possible mechanisms and significance of this conversion are discussed.
Key Word Index
Cannabis sativa - Saccharum officinarum - Cannabidiol - Cannabielsoin - Tissue culture - Suspension culture - Biotransformation